Key Nervous System Components Influence Gastrointestinal Tumor Growth
Research has found that common nervous system components are present in the gastrointestinal tract, where they influence tumor growth, revealing new opportunities for cancer treatment.
The gut has its own nervous system, often referred to as the "second brain." Neuropeptides, signaling factors produced and released by nerves, play a key role in this system. They relay messages throughout the nervous system by connecting to receptors on the outside of cells, influencing various processes.
- CGRP, a common neuropeptide, and its receptor RAMP1 have been found to influence tumor growth in colorectal and stomach cancers.
A team at the Olivia Newton-John Cancer Research Institute (ONJCRI) and La Trobe School of Cancer Medicine made this discovery, creating promising new avenues for treatment with existing approved therapies.
The gut contains its very own nervous system and is commonly regarded as the second brain.
Author's summary: Nervous system components influence gastrointestinal tumor growth.
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