Effect of Intensive Blood Pressure Lowering Treatment on Retinal Microvasculature: Secondary Analysis From ESPRIT | 2 Minute Medicine

Effect of Intensive Blood Pressure Lowering Treatment on Retinal Microvasculature

A secondary analysis from the ESPRIT study examines the impact of intensive systolic blood pressure (SBP) management on retinal microvasculature in high-risk populations.

Hypertension can cause damage to the retinal microvasculature, leading to hypertensive retinopathy, characterized by structural and functional changes.

Antihypertensive treatment has been shown to slow the progression of hypertensive retinopathy, but the benefits of intensive SBP management compared to standard treatment are unclear.

This multicenter, open-label, randomized controlled trial involved 2,518 patients with a mean age of 62.7 ± 6.4 years, 37% of whom were female.

Intensive systolic blood pressure management reduces hypertension-mediated retinal microvascular damage in populations with high cardiovascular risk.

Evidence rating level: 1 (Excellent)

Author's summary: Intensive blood pressure lowering treatment reduces retinal microvascular damage.

more

2 Minute Medicine 2 Minute Medicine — 2025-10-31

More News