A real-world analysis shows Shingrix effectively prevents shingles in adults over the age of 65, including immunocompromised people. Two doses provide better protection than one.
Shingles is a viral infection that occurs when the varicella-zoster virus (VZV) reactivates in the body, presenting as a rash with painful blisters. Although anyone can get shingles, it is more common in adults over 50, according to the CDC.
Shingrix, a recombinant zoster vaccine (RZV) manufactured by GSK, is effective in preventing shingles, with two doses being more effective than one. Between 5% and 30% of patients with shingles experience post-herpetic neuralgia (PHN), a long-lasting nerve pain.
Shingrix is effective in preventing shingles in adults over 65, including immunocompromised adults.
Author's summary: Shingrix prevents shingles in seniors.