The Food and Drug Administration (FDA) has approved updated indications for Rinvoq® (upadacitinib) in the treatment of adults with moderately to severely active ulcerative colitis (UC) or Crohn disease (CD).
Prior to this approval, Rinvoq had been indicated for adults with moderately to severely active UC or CD who had an inadequate response or intolerance to 1 or more tumor necrosis factor (TNF) blockers.
The updated indications now state that if TNF blockers are clinically inadvisable, patients may still be administered Rinvoq if they have previously received at least 1 approved systemic therapy.
Author's summary: Rinvoq gets FDA approval update.