Researchers conducted a prospective cohort study and Mendelian randomization to investigate the relationship between sleep apnea and age-related macular degeneration (AMD).
The study, presented at the American Academy of Ophthalmology annual meeting, found that patients with sleep apnea may be at greater risk of developing AMD.
Managing sleep apnea may modify the risk for AMD.
The investigators, led by Yuchen Lu, BS, combined large-scale cohort data with genetic analysis, finding strong evidence that sleep-disordered breathing may play a causal role in AMD pathogenesis.
Using Cox proportional hazards models, the researchers estimated AMD risk while accounting for potential confounding factors such as age, sex, smoking status, and comorbidities.
Author's summary: Sleep apnea is linked to a higher risk of AMD.