Melatonin and Heart Health
Scientists have discovered a surprising link between long-term melatonin use and heart failure in patients with chronic insomnia.
Melatonin, often referred to as "nature's sleep switch," has become a popular nightly habit for millions of people. However, new research presented at the American Heart Association's Scientific Sessions 2025 suggests that this supplement may have unintended consequences on the heart.
Marketed as nature’s sleep switch, melatonin has become a nightly habit for millions.
- Long-term melatonin use (for a year or more) was linked with a nearly doubled risk of developing heart failure.
- More than triple the risk of hospitalization for heart failure.
- Nearly twice the risk of death over five years.
This research is based on a review of more than 130,000 adults with insomnia.
Author's summary: Melatonin may harm heart health in insomnia patients.