Retinal Textural Changes on OCT May Show Early Diabetic Change
Retinal texture analysis using optical coherence tomography may aid early diagnosis of diabetic retinopathy, a study suggests.
An analysis of retinal textural changes on optical coherence tomography (OCT) imaging could potentially be used to identify early retinal alterations in patients with diabetes, according to data published in Eye & Vision (London).
The technique detects early retinal changes in animal models with type 1 and type 2 diabetes prior to observable clinical changes.
This information could aid in early diagnosis and improved prognosis in humans.
An animal model had previously demonstrated that retinal textural changes were observable during a longitudinal study where type 1 diabetes was induced in rats by a high-fat diet (HFD) and a low-dose intraperitoneal (IP) injection of STZ (35 mg/kg).
OCT and electroretinography (ERG) acquisitions were performed to detect changes, and an evaluation of molecular, cellular, and vascular parameters was performed.
Author's summary: Study suggests retinal texture analysis may aid early diabetic retinopathy diagnosis.
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